Safety Criteria And Markers For Remote Ambulatory Monitoring Of Pregnant Women With Hypertonic Syndrome

Abstract

For safe outpatient monitoring of pregnant women with hypertensive syndrome, markers for monitoring the state of the mother and fetus have been developed. Preeclampsia is a serious complication of pregnancy that affects the health of both the mother and the fetus. In a meta-analysis of genome-wide associations of European and Central Asian mothers, we identified sequence variants that are associated with preeclampsia in the maternal genome in ZNF831 / 20q13 and FTO / 16q12.In stationary conditions, 98 pregnant women with hypertensive syndrome and a burdened obstetric history were examined using 24-hour blood pressure monitoring (ABPM), dopplerometry of the fetoplacental complex and cardiotocography (CTG) in order to determine markers of hypertension. All patients with identical indications for hospitalization in hypertensive conditions were divided into 2 groups, depending on the outcomes of pregnancy. Group 1 consisted of pregnant women who were delivered within 3-5 days from the date of admission to the hospital and group 2 of pregnant women who prolonged pregnancy for more than 5 days and were discharged from the hospital. A comparative analysis revealed some markers that can be used for safe monitoring of the condition of a pregnant woman in an outpatient setting.